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Modern radiology and nuclear medicine can also provide multiple imaging biomarkers of the same patient, using quantitative data derived from all sources of digital imaging, such as CT, MRI, PET, SPECT, US, x-ray, etc. [20, 21].
Multiple imaging biomarkers such as T2 mapping, T1rho, and dGEMRIC demonstrated sensitivity to biochemical alterations of cartilage repair tissue.
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The ongoing head-to-head comparison of a large panel of biomarkers (a dozen biochemical biomarkers and multiple sensitive imaging biomarkers) through the OARS I/Foundationfor NIH study promises to provide much needed vital information for determining some of the best candidates for further qualification in clinical trial scenarios.
The availability of ADNI genetic data and multidimensional phenotypes from multiple imaging and biomarker modalities has enabled new discovery of promising candidate genetic variants which may serve as targets for development of disease-modifying agents or lead to enhanced diagnostic techniques and biomarkers.
Multiple prognostic and predictive imaging biomarkers have been identified.
Imaging biobanks are defined as organised databases of medical images, and associated imaging biomarkers (radiology and beyond), shared among multiple researchers, linked to other biorepositories [10].
The WG provided the following statements: (1) Imaging biobanks can be defined as "organised databases of medical images and associated imaging biomarkers (radiology and beyond) shared among multiple researchers, and linked to other biorepositories".
Oncologic imaging seems to be the easier setting for the collection of imaging biomarkers from multiple imaging modalities.
Imaging biomarkers, radiomics, radiogenomics, and imaging biobanks 6.
Imaging biobanks are "shared databases of imaging biomarkers, linked to biorepositories".
The White Paper on Imaging Biomarkers [1] asks for research fellowship programmes in quantitative imaging and biomarkers.
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