Future work will demonstrate this capability with microarrays and multiple fluorescence imaging applications.
Clinical use of these contrast-enhanced MRI scans has further expanded as multiple contrast agents have been approved for specific clinical imaging applications (e.g., blood pool contrast agents4, hepatobiliary contrast agents5).
Overall, DC-MRF provides an imaging platform that can be used to independently monitor multiple paramagnetic MRI contrast agents with numerous clinical and preclinical molecular imaging applications.
The utility of Cygnus to detect the cellular cGMP response to external application of SNAP was sufficient in the multiple imaging (Figure 2), but its signal amplitude is relative small.
Although nanospheres themselves appear unsuitable for in vivo imaging applications due to the short radiation penetration depth and low multiple-pulse damage threshold, other options for in vivo applications remain viable.
The successful application of BRT in the treatment of STS is dependent on multiple imaging modalities.
Successful application of BRT in the treatment of STS requires implementation of multiple imaging modalities for preprocedure planning, postoperative assessment of the accuracy of target volume coverage and integrity of the implant, as well as in three-dimensional treatment planning.
Successful application of brachytherapy in the treatment of soft tissue sarcoma requires implementation of multiple imaging modalities during preoperative and postoperative planning.
This study's hypothesis of obtaining multiple, stimuli-responsive optical signal changes using molecularly engineered inorganic NPs can further be expanded to drug delivery and other imaging applications.
We report increased signal-to-noise ratios and decreased false positive emission bleed-through using this novel multiple-excitation MPM (ME-MPM) compared to conventional single-excitation MPM (SE-MPM) in a variety of multi-color imaging applications.
