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In his riddle of induction, Goodman (1965) pointed out that for a set of observations, there will be multiple hypotheses that are equally supported.
They contribute an object tracking method that generates and maintains multiple hypotheses that consist of a probabilistic state estimate that is generated by the individual sources of information.
They were used to aid understanding of climatological, hydrological and model-based causes of differences in predictive performance by assessing multiple hypotheses that describe where and when the model was expected to perform best.
The interrelated multiple hypotheses that are presented for the first time in this article are extension of author's earlier series of 'accidental' discoveries on the role of inflammation in developmental stages of immune dysfunction toward tumorigenesis and angiogenesis.
In the presence of noise, either white or due to frequency components that are not part of the model (e.g., the noise of the bow scratching the strings of a violin), it is possible to find multiple hypotheses that may explain the partials found in a specific frame [21, 68].
In addition to examining multiple hypotheses that are specified a priori, these studies also constitute a resource for subsequent nested case-control and case-cohort analyses.
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In light of these pitfalls, we recommend that long-term monitoring studies on kittiwakes and other seabirds carefully consider in their study designs and implementations multiple working hypotheses that might explain major changes in breeding success.
It informs attempts to culture the symbionts and generates multiple intriguing hypotheses that now await experimental validation.
It is our hope the future studies that seek to identify the molecular mechanisms causing the myriad phenotypes presented in these mutants may be facilitated by the gene networks reported in this study and the multiple testable hypotheses that arise from them, for example the predicted function of sticky kinase and Fmrp in cell polarity and DNA damage repair.
Automated procedures of model simplification, however, often make us forget that this constitutes a case of multiple hypotheses testing that will lead to high rates of type I errors (Zhang 1992; Whittingham et al. 2006; Mundry and Nunn 2009) as well as biased effect size estimates (Burnham and Anderson 2002; Lukacs et al. 2010).
These data are uncorrected for multiple hypotheses, given that these SNPs have been associated with T2D in populations of European descent (Table S1).
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Justyna Jupowicz-Kozak
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