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Care will be taken to avoid discovery of spurious relationships by leveraging the size of our data to correct for the multiple hypotheses tested during exploratory analyses.
Next, we calculated the False Discovery Rate (FDR) to adjust the p-values given the multiple hypotheses tested.
Second, we applied the false discovery rate to quantify uncertainty across the multiple hypotheses tested in the six single marker tests and the multiple haplotype tests.
It is difficult to reliably estimate many parameters, and correctly infer associations from multiple hypotheses tested simultaneously.
The step-down max T adjustment is used to calculate adjusted p values to account for the multiple hypotheses tested.
Importantly, I am not convinced that many of the results reported are statistically significant since given the multiple hypotheses tested some correction is necessary.
Similar(50)
P values were determined by a one-tailed Fisher's exact test and the Benjamini Hochberg method was used to correct for multiple hypotheses testing.
Results were adjusted for multiple hypotheses testing using the FDR for each functional group/pathway.
The p-values are corrected for multiple hypotheses testing using the false discovery rate procedure [33].
P values were corrected for multiple hypotheses testing using the false discovery rate test (FDR, 5%).
Z-test p-values were corrected for multiple hypotheses testing using the Bonferroni method.
More suggestions(15)
multiple pathways tested
multiple clones tested
multiple genes tested
multiple fractions tested
multiple outcomes tested
multiple epitopes tested
multiple regions tested
multiple lineages tested
multiple occasions tested
multiple samples tested
multiple subtypes tested
multiple comparisons tested
multiple probes tested
multiple sites tested
multiple hypotheses analysis
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com