Sentence examples for multiple human tumors from inspiring English sources

Mutant RAS oncoproteins activate signaling molecules that drive oncogenesis in multiple human tumors including acute myelogenous leukemia (AML).

Given the clinical relevance of maspin expression in a variety of epithelial tumors (including breast, prostate, lung and colon cancer), these studies describe a novel approach to target multiple human tumors [141 148].

TGF-β derived from cancer-associated fibroblasts upregulates CXCR4 in initiated prostatic epithelial cells [38], and expression of CXCR4 correlates with lymph node metastasis in multiple human tumors [39].

We recently demonstrated that HSF1 is highly expressed in multiple human tumors including lung, colon, breast, and ovarian cancers.

While the presence of CSCs has been documented in multiple human tumors, the mechanisms that regulate CSCs remain to be fully elucidated.

Given that EGFR is a critical molecule linked with multiple human tumors, our findings may have many important clinical implications (Ciarmela et al. 2011).

The coding sequences of multiple human tumor suppressor genes include microsatellite sequences that are prone to mutations.

PTK6 is expressed in multiple human tumor types, including breast and ovarian tumors [14] [16], [18].

To compare the expression levels of TMEFF2 in human tissues, we analyzed Affymetrix microarray data obtained from GeneLogic, Inc. (Gaithersburg, MD) containing multiple human tumor and normal tissue samples.

Accordingly, inhibiting this signaling axis by the use of specific small molecule inhibitors of JAK2 has recently been investigated as a point of therapeutic intervention in multiple human tumor indications [3], [21], [22], [23], [24].

CI-1040 blocks ERK phosphorylation and inhiblockshERKrowth of multiphosphorylation cell lines and tumor growth inhibitsraftheodels.