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These adaptations evolved in parallel in multiple human populations, providing a chance to investigate independent realizations of the evolutionary process.
The 100 Genome Project will soon provide the genome variation in multiple human populations [25].
Based on these data, we refined the region associated with prostate cancer risk to a 15 Kb LD block and revealed strong signatures of selection in multiple human populations and, possibly, other primate species.
In addition, the detailed catalog of genetic variation it provides across multiple human populations has been used to understand the processes affecting specific genes.
Several independent studies have identified and replicated genomic regions that contain risk variants for prostate cancer in multiple human populations [ 30- 33].
This hypothesis proposes that risk alleles for common complex diseases should be common (i.e. ≥ 5%) and thus are likely old and found in multiple human populations, rather than being population specific [ 1- 4].
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They are suitable for the design of epitope-based vaccines because they can interact with multiple HLA within human populations.
For example, the persistence of the ability to digest lactose after the weaning phase has arisen independently multiple times in human populations characterized by a history of cattle herding.
The diversity of human cultural groups in which art coevolves requires that we recognize that there are multiple human "artworlds" with different populations of interacting producers and observers.
In multiple studies of unrelated human populations, Foxo3a variants have been associated with increased survivorship more extensively than polymorphisms for any other gene or locus (Willcox et al., 2008; Anselmi et al., 2009; Flachsbart et al., 2009; Li et al., 2009; Pawlikowska et al., 2009; Soerensen et al., 2010; Ziv & Hu, 2011; Däumer et al., 2014).
These new strategies will need to accommodate multiple human impacts on the population and ecosystem as part of the efforts of HELCOM, ICES, and the European Union (EU) to move toward EBM in this region [112].
More suggestions(15)
many human populations
multiple human actions
multiple human motions
multiple human samples
multiple human figures
multiple human diseases
multiple human alterations
multiple human values
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multiple human skulls
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