Sentence examples for multiple human malignancies from inspiring English sources

These findings reveal a potential carcinogenic role of GNA13 in multiple human malignancies.

Epigenetic and post-transcriptional inactivation of this protein is commonly observed in multiple human malignancies, and can potentially favor progression of tumors driven by a variety of genetic mutations.

Dysregulation of Wnt-β-catenin signaling underlies multiple human malignancies [68].

The constitutive expression of OPN has been reported to be involved in the process of tumor carcinogenesis and metastasis of multiple human malignancies [38].

Elevated MIF levels occur in multiple human malignancies.

This NPM expression in multiple human malignancies implicates that NPM might play an important role in tumorigenesis and development.

Inhibition of Aurora kinases promotes G2/M arrest and apoptosis in multiple human cancers including lymphoid malignancies (multiple myeloma and adult T-cell leukemia), but no data are available, which suggest a role of Aurora kinases in Hodgkin lymphomagenesis.

XBP-1 is upregulated in many human malignancies, particularly multiple myeloma, a cancer for which few treatment options are available.

Indeed, increased levels of IGF1 and IGF1R have been documented in multiple types of human malignancy.

Cyclin D1 oncogene activation is a prevalent molecular driver of human cancer, playing key roles in breast, squamous cell, esophageal carcinoma, mantle cell lymphoma, multiple myeloma, and many other devastating human malignancies.

We conclude that modulation of drug sensitivity by rhEGF is observed in cell lines representative of many human malignancies and for multiple classes of chemotherapeutic agents, indicating that it alters one or more components of the cellular damage response that are both common between cell lines and classes of drugs and fundamental to survival.