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We have developed a procedure for massively parallel resequencing of multiple human genes by combining a highly multiplexed and target-specific amplification process with a high-throughput parallel sequencing technology.
To test whether dLbCpf1-p300core proteins could be used to simultaneously activate multiple human genes with a minimal number of gRNAs, we examined the capability of single gRNA to activate gene.
These findings show that environmental chemicals are active across multiple human genes and pathways.
Some of the mouse genes were found to be correlated to multiple human genes.
This resulted in 137 distinct mouse genes (several mouse genes were correlated with multiple human genes, which is expected if the human genes are co-expressed).
For other regions we tested orthologs of multiple human genes, and at six of the remaining regions our sucrose toxicity screen implicated a single human gene ortholog.
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In order to assess the effectiveness of the proposed algorithm on extracting biological modules from multiple gene coexpression graphs, we performed an experimental evaluation of the algorithm using multiple human gene expression datasets.
The targeted knockin of multiple human cytokine genes into their respective loci within mice would be anticipated to further improve tumor engraftment.
The coding sequences of multiple human tumor suppressor genes include microsatellite sequences that are prone to mutations.
In this study, we described a rapid, reproducible, and relatively inexpensive approach allowing the detection of multiple human methylated promoter genes from many tissue samples, without the need of bisulfite conversion.
EST matches to multiple horse or human genes were excluded.
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multiple human genome
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