Sentence examples for multiple human cancer from inspiring English sources
The biological activity of these novel synthetic compounds was tested against multiple human cancer cell lines: breast cancer cell lines MCF-7, BT-20, MDA-MB-231 and prostate cancer cell line PC-3, all of which differ in their expression of RAR subunits.
Defects in genes required for DNA replication and repair always cause genetic instability and are associated with multiple human cancer types (Preston et al., 2010).
Excess iron is tightly associated with tumorigenesis in multiple human cancer types through a variety of mechanisms including catalyzing the formation of mutagenic hydroxyl radicals, regulating DNA replication, repair and cell cycle progression, affecting signal transduction in cancer cells, and acting as an essential nutrient for proliferating tumor cells.
The search results revealed that EZH2 is consistently upregulated in multiple human cancer types including breast cancer, while CDKN1C is downregulated in these tumors (Figure 6A).
To determine whether thiostrepton may synergize with bortezomib against human cancer cell lines of different origin we treated multiple human cancer cell lines with either sub-apoptotic concentrations of thiostrepton or bortezomib alone or with combinations of the two for 24 hours and used caspase-3 to serve as an indicator of apoptotic cell death (Figure 1).
Current studies revealed that the dysregulation of miR-125 occurs in multiple human cancer types [ 9– 13].
Burns, M.B., Temiz, N.A. & Harris, R.S. Evidence for APOBEC3B mutagenesis in multiple human cancers.
Morris, L.G. et al. Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation.
Ginkgo biloba extract (GBE) has exhibited antitumor activity in multiple human cancers.
Mutations within the ING1 gene and altered expression levels of ING1 are found in multiple human cancers.
Our results identify a strong candidate tumour suppressor gene at chromosome 10q23.3, whose loss of function appears to be associated with the oncogenesis of multiple human cancers.
