Sentence examples for multiple high affinity from inspiring English sources

Previous studies have demonstrated that Ikaros binds to heterochromatin through multiple high affinity binding sites [49], [64].

This property of SSB is possible owing to multiple, high affinity binding sites distributed around the tetramer, or as the case may be in the high-salt mode, octamers.

Our data provide direct evidence for multiple high affinity couplings for all GLP-1 receptor agonists and establishes the yeast platform as a robust tool to screen for more selective highly efficacious mimetic compounds in the future.

Entry 4 shows a β-hairpin found in the Rap30/Rap74 complex of human transcription initiation factor IIF. Entry 5 shows a pair of nonhairpin strands from the HTH-type transcriptional regulator LRPC, as an example of a complex in which one chain possesses multiple high affinity strands without that do not participate in a hairpin relationship.

The results corroborate evidence for these binding interactions and indicate multiple high-affinity modes of binding.

Using new high-throughput procedures and the most complex library, we produced multiple high-affinity antibodies with dissociation constants in the single-digit nanomolar range against a wide variety of protein antigens.

In summary, invasion of keratinocytes by S. aureus requires multiple high-affinity FnBRs within FnBPA, and given the importance of the interaction between these cell types and S. aureus for both colonisation and infection, may have provided the selective pressure for the multiple binding repeats within FnBPA.

Docking simulations provided corroborating evidence for these binding interactions and indicated multiple high-affinity modes of binding.

Second, for multiple high-affinity binding sites (experimentally determined using methods such as ChIP, SELEX and PBM) we will use the PFM.

However, a closer investigation of the binding profiles at loci containing multiple high-affinity binding motifs (promoter regions of Sso0049 and mtaP) confirmed complete absence of Ss-LrpB-specific enrichment in these regions.

Using a rational drug design approach, we took advantage of the multiple high-affinity nucleobase uptake transporters in the T. brucei parasite for selective delivery of toxic cargo into the parasite.