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Mass measurements indicated that both peptides had multiple heptose modifications; a mixed population of modified peptides, containing different numbers of heptose conjugations, was observed.
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The alteration in LOS structure seen in the commensal organisms suggests that the third heptose modification may play an important role in modulation LOS/LPS mediated toxicity.
The major advantage that this approach provides is the capacity to introduce multiple genetic modifications concurrently.
Zhou, J. et al. One-step generation of different immunodeficient mice with multiple gene modifications by CRISPR/Cas9 mediated genome engineering.
Ota, S., Hisano, Y., Ikawa, Y. & Kawahara, A. Multiple genome modifications by the CRISPR/Cas9 system in zebrafish.
1) Developing new technologies to rapidly assess the role of multiple epigenetic modifications in T cell function.
Multiple genetic modifications were made to the genome.
Multiple surface modifications have been studied to prevent bacterial growth on implants.
Multiple genetic modifications in pigs can essentially benefit research on agriculture, human disease and xenotransplantation.
This variability originated from different histone variants as well as from diverse and multiple peptide modifications.
In vertebrates, Drp1 is subjected to multiple posttranslational modifications, including phosphorylation, ubiquitination and sumoylation [26].
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