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At traditional ceremonies, multiple healthy individuals can be exposed to highly infectious bodily fluids of a deceased patient.
The gates for WT1 tetramer+ cells were drawn as <0.1% of CD8+ T cells were included in the tetramer-positive gate in multiple healthy individuals (Supplementary Figure 1A).
An alternative approach to the concern of variation would be to utilize multiple stem cell clones from each individual patient and compare the desired measurement against multiple healthy individuals.
Lymphocytes isolated from pooled blood of multiple healthy individuals were cryopreserved in DMSO and glycerol for periods of 7, 14, 30, and 60 days and were challenged with LPS and LTA in vitro.
It is possible, then, that F941V and/or G1145S have variable effect sizes on other CR3 functions, such as the inhibition of Toll 7/8-induced proinflammatory cytokines; however, in the absence of ex vivo cells from multiple healthy individuals carrying these mutations, or additional suitable in vitro assays, we lack a sufficient model for this [ 19, 43].
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CA-MRSA causes skin and soft-tissue infections such as multiple abscesses among healthy individuals, as well as life-threatening necrotizing pneumonia in children and young adults [1].
As multiple tissue analysis in healthy individuals is highly complicated, data on whole body mtDNA heteroplasmy is still far from clear.
Recent computational models and experimental probes support the notion of multiple learning mechanisms in healthy individuals [ Chiu et al., 2008; Daw et al., 2011; Glascher et al., 2010; Lohrenz et al., 2007; Montague et al., 2004, 2006; Pagnoni et al., 2002; Simon and Daw, 2011].
To investigate whether (1) resting body temperature is elevated in patients with relapsing-remitting multiple sclerosis (RRMS) relative to healthy individuals and patients with secondary progressive multiple sclerosis (SPMS), and (2) warmer body temperature is linked to worse fatigue in patients with RRMS.
We therefore analyzed sera from 36 CFS patients, 112 multiple sclerosis patients and 27 healthy individuals for serological evidence of XMRV infection (Table 1).
In AL, λ is overrepresented (3∶1) as compared to healthy individuals or multiple myeloma patients (λ/κ = 1∶2), especially the λ VI subtype [5].
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