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As well, it will add great value if multiple grading systems are used within a single dataset and molecular differences assessed between the different systems.
These multiple grading systems do, however, agree on the histologic parameters that are important in the determination of glioma biology, namely hypercellularity, pleomorphism, vascular endothelial proliferation, mitotic activity and necrosis.
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Rural schools are often so small that one instructor must be responsible for multiple subjects, and sometimes multiple grades.
The death of the multiple grade I winner Nashoba's Key on Wednesday is one more sad example of this.
Rachel Alexandra was sired by Medaglia d'Oro, a multiple Grade I winner who retired with career earnings of more than $5.7 million.
He is a multiple graded-stakes winner who earned more than $1.1 million over a nine-year career.
"I'm taking very seriously the suggestion of grading various categories," he said, responding to the suggestion that the city use multiple grades for each school.
This gives a chance to hone your skills before hitting the "washing machine" (grade two) on day three and the multiple grade-one rapids on day four.
The trainer said the problem corrected itself without intervention and hopes the multiple Grade One winner will be back in action next season.
See You in the Fall: More Teachers and Classes Are Staying Together for Multiple Grades" (news article, July 11): I was delighted to read about the experience of Leslie Cohen, a kindergarten teacher, with "looping".
It was also a tough afternoon for the multiple Grade I winner Harlan's Holiday, who was making his first start since finishing second in the Dubai World Cup on March 29.
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