Sentence examples for multiple genome contigs from inspiring English sources
From BLASTN searches (E-value ≤ 1E-10), a total of 159 genes were hit by multiple genome contigs.
Median sequencing coverage for single-copy contigs was 50× (i.e. close to the calculated average sequencing coverage, 67×), while multiple-copy genome contigs had generally higher coverage with median at 880× (Additional file 2: Figure S2).
RAD loci or PE contigs aligning to multiple (> 2) reference genome contigs were excluded.
A multiple genome alignment of the assembled contigs of the 18 human isolates as well as the publicly available genomes of human isolates was calculated using the progressiveMauve algorithm implemented in the program Mauve (version 2.3.1) [ 47] and SNPs were identified by Mauve.
The signal sequence motif was identified in 27 distinct S. japonicum UniGene entries with multiple mRNA transcripts, and in 34 genome contigs distributed within 18 scaffolds with evidence of genome-wide dispersion.
A multiple genome alignment was conducted by aligning contigs from the different assemblies to the PacBio reference assembly to identify conserved regions and to evaluate gaps in the different DSM 10061 assemblies.
It should be noted that many of these ISVs have multiple genome segments and homology was often quite low, making it challenging to confidently ascribe contigs to distinct putative new ISVs.
It should be noted that since most bee genome contigs have not be scaffolded, it is possible that one protein may span multiple contigs; thus, some of the novel, expressed ORFs detected here may come from the same protein.
We wrote a PERL program, PolyMFind, to parse this multiple genome alignment and scan for aligned positions with a SNP, a gap, or an "N" (nucleotide inserted between contigs to stitch them together).
Furthermore, metagenomic assembly 'obscures' the population microdiversity by delivering consensus genome contigs that hide the extant genetic heterogeneity.
Multiple genome alignment remains a challenging problem.
