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Here we report multiple genome aberrations in a collection of 78 CML and 14 control samples by oligonucleotide array comparative genomic hybridization.
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If there were multiple genomic aberrations, the lineage of multiple tumors could be deduced from the patterns of the aberrations.
Sequencing of targeted gene panels may be useful in uncovering multiple genomic aberrations using a single test.
HCC encompasses different pathological manifestations and etiology coupled with multiple genomic aberrations leading to high heterogeneity and intractable treatment.
Genome aberrations in cancer cells can be divided into two types: random 'passenger mutation' and functional 'driver mutation'.
Multiple genome alignment remains a challenging problem.
Multiple genome alignments are downloaded from UCSC Genome Browser [22].
As it is well known, same pathway may result from different genome aberrations [ 11, 12].
This ranges from studies looking at genome aberrations in cancer or tumour cells to genome diversity in bacterial cells.
Discrete routes of pathway activation or inactivation determined by cancer genome aberrations are treated as separate cohorts.
Radiation-induced genome aberration has a crucial role in the mechanisms underlying radiation-induced carcinogenesis.
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