Sentence examples for multiple genetic targets from inspiring English sources

However, various disadvantages and limitations arise when the detection of multiple genetic targets is required.

This approach limited the number of analyses required and was amenable to testing multiple genetic targets simultaneously (i.e., spiking a single sample with multiple microorganisms).

Selection systems involving dapB (dihydropicolinic acid reductase) have been reported for other Gram negative pathogens such as Burkholderia pseudomallei, thus it appears there are multiple genetic targets to block this highly conserved metabolic pathway [13], [14].

The use of stringent ancient DNA protocol, multiple genetic targets with 100% sequence homology to pathogenic targets and a cognitive approach to authentication of mitochondrial DNA sequence analysis, sex and familial relatedness results was used to ensure authenticity of our ancient DNA results [39].

Its diverse clinical characteristics illustrate the complexity of the disease, involving several dysregulated metabolic pathways and multiple genetic targets.

On account of the fact that microsatellites are widely distributed in our genome, mutations of MMR genes affect multiple genetic targets, as those described in mononucleotide repeats of the DNA double-strand breaks (DSBs) repair genes BLM, ATR, DNA-PK, BRCA2, RAD50, and MRE11.

This study shows that a combination of a multiplex PCR assay, viral antigen, and/or culture should be used to detect variants of RSV in patients and that multiplex respiratory viral assays should develop a more robust design that includes multiple genetic target per virus to prevent missing viruses that continue to have genetic variances.

Considering the complexity of breast cancer, with its multiple genetic abnormalities, targeting a single pathway by inhibiting the activity of one component is unlikely to be effective in a long term.

Since it is known that breast cancer is a clinically heterogeneous disease with multiple genetic abnormalities, targeting and inhibiting Hsp90 has been considered an effective strategy for breast cancer therapy [ 5].

Since breast cancer is a clinically heterogeneous disease with multiple genetic abnormalities, targeting a single pathway in cancer cells by inhibiting the activity of a single component is not likely to be effective in the long term treatment for the cancer.

As a result, multiple genetic pathways and targets were identified as significantly down- or up-regulated.