Sentence examples for multiple genetic polymorphisms from inspiring English sources

Multiple genetic polymorphisms involving 5-HTT regulatory sites reportedly increase the vulnerability for developing mood disorders (reviewed in Cannon et al. 2007).

Rather than polymorphisms in single genes, the interaction of multiple genetic polymorphisms in low penetrance genes involved in genotoxic effects might be of relevance.

BCERC investigators are using new technologies to assess gene and protein expression to elucidate the effects of multiple genetic polymorphisms, including those affecting hormone synthesis and metabolism and carcinogen metabolism.

It is important to compare findings across studies to validate results and to detect relatively weak statistical associations that are commonly found when multiple genetic polymorphisms make small contributions to common disorders.

It is thus crucial to assess multiple genetic polymorphisms simultaneously, in order to obtain a better insight in human susceptibility, and thus longevity, in response to exposures to genotoxic substances.

Under this model, the influence of multiple genetic polymorphisms on the FVB/N background would hasten the development of these architectural features, resulting in premature age-related thymic involution.

However, more work needs to be done on complex interactions involving multiple CYPs, some with genetic polymorphisms, and transporter processes.

This is the first investigation of clinical outcome using multiple chemotherapeutic drug-related genetic polymorphisms for Taiwanese patients with advanced CRC.

In the long run, multiple genetic traits, such as polymorphisms related to TCF7L2 (21– 24), FOXO1 (25), and WFS1 (26); potassium channels associated with sulfonylurea receptors (5); and many more aspects of β-cell mass and function, including parameters related to insulin resistance, may as a whole help predict the individual response to specific glucose-lowering treatments.

However, the impact of control efforts remains difficult to measure due to the inherent complexities of HFRS as a disease: multiple viral strains with identified genetic polymorphisms, complex disease manifestation, diverse animal reservoirs, and multiple routes of transmission [ 8].

Multiple studies have demonstrated that genetic polymorphisms may influence the expression of genes or the functions of gene products and affect the susceptibility of VKH disease (Tables 4 and 5).