Sentence examples for multiple genetic modification from inspiring English sources
Therefore, multiple genetic modification approaches aim at improved substrate utilization and decreasing byproduct formation (Nissen et al., 2000a, b, 2001; Kong et al., 2006, 2007; Zhang et al., 2007).
Multiple genetic modifications were made to the genome.
The ability to breed pigs with multiple genetic modifications provides a unique opportunity to explore the immunologic challenges of pulmonary xenotransplantation.
In the present work, two novel proprietary heterologous genes (MGT05196 N360F and Ru-xylA) were combined with other multiple genetic modifications and three rounds of adaptive evolution to engineer the diploid S. cerevisiae chassis strain BSIF.
Multiple genetic modifications in pigs can essentially benefit research on agriculture, human disease and xenotransplantation.
Since multiple genetic modifications in a short timespan might be considered rare, a single genetic modification probably occurred to elicit this response, in the e-cadherin pathway or an alternate that directly affects e-cadherin.
For the achievement of some specific transgenic phenotypes, multiple genetic modifications need to be completed through sequential modifications in primary cells prior to nuclear transfer [ 25].
The development of the GS1.11-26 strain has shown that introduction of efficient D-xylose fermentation capacity in an industrial yeast strain requires multiple genetic modifications [ 27].
The feasibility of the GEMM-ESC approach is supported by recent reports on the successful generation of chimeric mouse models for breast cancer and non-small cell lung cancer (NSCLC) based on step-wise introduction of multiple genetic modifications into wildtype ESCs [ 8, 12].
Furthermore, the improved tolerance to multiple inhibitors was conferred by genetic modification of the relevant genes in S. cerevisiae (Fig. 1).
In 1991, two seminal papers (Bailey, 1991; Stephanopoulos & Vallino, 1991) introduced a novel systematic approach of genetic modification where multiple genes were targeted, termed 'metabolic engineering'.
