Sentence examples for multiple genetic contexts from inspiring English sources

These observations suggest the importance of conducting siRNA screens against multiple cell types in order to corroborate results across multiple genetic contexts and, ultimately, to reduce contradictory observations when merged with text mining results.

By studying a fine gradient of copper at a high experimental power in multiple genetic contexts, we have captured a more fine-grained view of transcriptomic variation in S. cerevisiae in response to copper than previously available.

Here, we test whether the interacting mutations will differentially affect a variety of traits in multiple nuclear genetic contexts.

While increasingly sophisticated animal models are being used to define discrete mechanisms by which fibroblasts contribute to tumor progression, these models are not well-suited for systematic discovery across multiple genetic and epigenetic contexts [3] [6].

Multiple genetic differences were found in the context of plant and human pathogenicity, notably the pro-inflammatory potential of A. alternata.

The functional impairment of a few nodes, which control directly or indirectly the activities of many others in the context of the co-occurrence of multiple genetic defects, could represent a selective advantage during neoplastic transformation (Additional file 12).

The specific value of PacBio and ONT sequencing is that they provide read lengths that are long enough to span multiple prokaryote genes and thus are able to provide reliable genetic contexts.

This is even more true in the context of multifactorial diseases, for not only are multiple genetic variants, each with their own effect sizes, involved in the causation of multifactorial diseases, there are also environmental factors at play.

Such culture systems are optimally suitable for the exploration of pathogenic events within a context of manageable complexity that can be subjected to multiple genetic, pharmacological, toxicological, or physical perturbations.

This work describes a representative case study for the debugging of genetic context-dependent effects through principles elucidated herein, thereby providing a rational design framework to integrate multiple genetic circuits in a single prokaryotic cell.

The context of this paper is that there are measurements on multiple genetic variants and several associated risk factors, the causal effect of at least 1 of which on the outcome is of interest.