Sentence examples for multiple genetic aberrations from inspiring English sources

Although tumors usually harbor multiple genetic aberrations [1], inhibition of only one or a few gene products can be sufficient to largely suppress tumor cell proliferation or viability [3].

Hepatocellular carcinoma (HCC) is a complex and heterogeneous tumor with multiple genetic aberrations.

Multiple genetic aberrations in FGFRs leading to increased pathway activation have been identified in breast cancer.

We can deduce how individual tumors evolved from common ancestor cells by comparing the aberration patterns of multiple genetic aberrations.

It is now accepted that accumulation of multiple genetic aberrations can lead to the development of most carcinomas.

It is currently realized that multiple genetic aberrations accumulating during the long process of carcinogenesis are responsible for the initiation and progression of cancers [ 6].

Cancer is associated with multiple genetic and regulatory aberrations in the cell.

Endometrial cancers develop through accumulation of multiple genetic and epigenetic aberrations.

Lymphomagenesis is a multistep process which involves accumulation of multiple genetic and epigenetic aberrations over a period of time.

Ovarian cancer (OC) comprises vast heterogeneity, with multiple genetic and epigenetic aberrations, and can be robustly characterised into distinct subtypes based on its molecular characteristics.

We conducted a regularized elastic-net regression analysis of heterogeneous genomic data that encompassed multiple classes of genetic aberrations (i.e. genomic features) in colorectal cancer.