In subsequent studies, Dr. Christiano and other colleagues identified multiple genes that play an important role in alopecia areata.
The HIF complex activates the transcription of multiple genes that are necessary for the Warburg effect to occur [12].
Genome-wide association studies (GWAS) point to allelic variants in multiple genes that confer susceptibility to RLS/WED.
However, several of the enzymes are encoded by multiple genes that are regulated differently, adding unexpected genetic complexity.
Genetic analyses of patients with neurodegenerative disorders have identified multiple genes that need to be investigated for the presence of damaging variants.
These include three new types of "pathogenicity islands," stretches of DNA with multiple genes that promote infection or stimulate immune responses in people.
Regarding the genetic basis of the QTL clusters, two main possibilities are generally considered: the pleiotropic effects of one or a few genes, or the effects of multiple genes that are tightly linked to one another.
Compared to conventional treatments, gene therapy offers a variety of advantages for cancer treatment including high potency and specificity, low off-target toxicity, and delivery of multiple genes that concurrently target cancer tumorigenesis, recurrence, and drug resistance.
While there he also started a new medical school, led many worldwide clinical trials to advance care for patients with heart disease, and spearheaded the discovery of multiple genes that increase susceptibility for heart attacks.
These findings suggest an attractive possibility that valproate increases expression of multiple genes that have protective effects against bipolar disorder.
Lastly, it is possible that the drugs may be targeting multiple genes that are playing roles in viral infection.
