We generated transgenic rice by introducing multiple genes, including ferritin under the control of endosperm-specific promoters, NAS overexpression, OsSUT1 promoter-driven OsYSL2 expression, and the barley IDS3 genome fragment, and showed increased concentrations of bioavailable Fe.
Prior mouse models for PWS include three different strains of deletion mice that affect expression of multiple genes including the snoRNA region.
Phylogenetic analyses of multiple genes, including the mating loci (HMG, TPT, RNA helicase), ITS1-5.8S-ITS2 rDNandRPB2, and LDH genes, identified two distinct groups of strains.
In colon cancer, previous studies have demonstrated a synergistic interaction between KRAS mutations and hypoxia in the regulation of multiple genes including VEGF [2], [8], [9].
In yeast the transcription of multiple genes, including GAL and HXK1, has been shown to be localized to the nuclear pore upon activation [44], [45], [46].
Numerous attempts at determining susceptibility genes through a number of large consortia have indicated that multiple genes, including immune related genes, may be associated with autism.
Phenotypic classification (types I to V with multiple genes included in some of the types) has been proposed.
The most comprehensive taxon sampling across angiosperms using multiple genes includes a study using atpB and rbcL [ 24] and a 567-taxon study with 18S rDNA, atpB, and rbcL [ 1- 3].
Datasets including multiple genes include all Mitochondrial genes (MA), fourfold degenerate sites (4ds) of mitochondrial genes (M4), 4ds site of nuclear genes with no evidence of positive selection (N4N), 4ds sites of nuclear genes having evidence of positive selection (N4S) and 4ds sites of all nuclear genes (N4A).
By qRT-PCR, we confirmed that overexpression of ETV2 induced expression of multiple vascular genes, including KDR, TAL1, PECAM1 and TEK (Fig. 1D).
The resulting gene fusions involve the TFE3 transcription factor gene and multiple reported genes, including the same one (ASPL) found in the characteristic gene fusion of alveolar soft part sarcoma.
