Sentence examples for multiple genes implicated from inspiring English sources

Myriad had already announced that it would begin, this fall, to replace its BRCA test with one that examines multiple genes implicated in hereditary cancers — most of which were outside the scope of its gene patents before Thursday's ruling.

Inspection of the basal transcriptome differences between CMP and control cells revealed the significant regulation of multiple genes implicated in neurodegenerative processes (SPAST, SACS, FKTN, DOPEY2, ALS2CR14, RTN3, BLZF1, SFRS11, AHR, ARPP-19, B2M), control of cytoskeletal dynamics (PTMA, DAPP1, HMMR, CAPZA1) and age-related energetic/metabolic changes (TSC1, LARS, MSTO1, LEP, SBDS).

In addition to collagen, multiple genes implicated in fibrogenesis showed substantial decrease in expression.

Multiple genes implicated in immune defense were differentially affected by infection in virgins compared with mated females (Table 3).

Microarray data further demonstrate that miR-663 suppresses the expression of multiple genes implicated in neurogenesis, including FBXL18 and CDK6.

In addition, functional annotation was also performed in CGH data, identifying multiple genes implicated in the previous described pathways (data not shown).

p53 is a potent transcription factor, which is activated following stress and regulates multiple downstream genes implicated in cell cycle control, apoptosis, antiangiogenesis and senescence.

The present study validates the approach of using a short dsRNA molecule specifically designed with a single guide strand to suppress the expression of multiple unrelated genes implicated in a particular medical condition.

Several factors made this gene an attractive candidate, including its frequent inactivation in human tumors, the observed lack of toxicity of wild-type p53 itself, the control that it exerts in multiple other genes implicated in apoptosis and cell cycle regulation, and some experimental evidence for a bystander effect.

TLE is currently considered to be a multifactorial disease, with multiple genetic susceptibility genes implicated and complex gene-environment interactions [5], [6] interplaying to determine disease onset and progression.

Unlike PCD, where multiple genes are implicated in the disease mechanism, variants in only few genes are currently known to cause isolated, non-syndromic laterality defects.