Sentence examples for multiple gene variants from inspiring English sources

Analyses utilizing the integrated information from multiple gene variants such as haplotype analyses may be beneficial as suggested by recent studies [10 12].

A. niger has a high capacity for degrading the hemicellulose, pectin and, to a lesser extend, cellulose fractions as the genome of A. niger encodes multiple gene variants of the enzymes required for the efficient degradation of these polysaccharides.

Hereditary predisposition to cancer is sometimes due to a single high-risk genetic change, like a mutation in the BRCA1 or BRCA2 genes for breast cancer, but most of the time, the disease is the result of multiple gene variants that add up, environmental risk factors, and a big element of chance.

We also show that multiple SNP variants in these pathways can be used to build predictive models of disease risk, thus providing a new picture of how multiple gene variants combine to contribute to disease risk.

We postulated that the genetic contribution to common inflammatory diseases would be determined by multiple gene variants in the same inflammatory pathways involved in host response to infectious diseases (Figure 1).

Recently, several GWAS have identified multiple gene variants that are associated with AD (reviewed in [ 19]).

This study investigates the relationship between schizophrenia susceptibility genes and schizophrenia sub-phenotypes by identifying multiple gene variant interactions.

The PRS approach relies on the theory that heritability, i.e. the amount of phenotypic variation explained by genetic components, of complex traits, is caused by an additive effect of multiple common gene variants with small effect sizes, a so-called polygenetic effect that is traditionally identified by GWAS.

In contrast to Mendelian disorders that are usually caused by single gene defects and often manifest with serious physical and/or intellectual abnormalities without effective cures, predisposition to functional psychiatric illnesses is generally associated with multiple susceptibility gene variants with small to modest effects [32].

Genetic risks likely also include multiple common gene variants of small effect size that have yet to be identified, with the possible exception of a few dopaminergic genes.

Here we indicate that tandem gene arrangements and the occurrence of multiple transcribed gene variants are common and indicate potentially complex genomic arrangements in O. marina.