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The present study describes novel, convenient strategies via rAAV-mediated multiple gene transfer to modulate the chondrogenic differentiation processes in human bone marrow concentrates for the treatment of damaged articular cartilage.
Specifically, multiple gene transfer events from cyanobacteria and chlamydiae (i.e. obligate intracellular pathogens AKA 'energy parasites') led to the evolution of chloroplast recAs.
Regarding recA, we infer multiple gene transfer events from cyanobacteria leading to the evolution of chloroplast recA, in accordance with the origin of chloroplasts from cyanobacterial ancestors [ 32].
We hypothesise that, when several GIs reside in a single genome, it is possible that a single donor has been responsible for multiple gene transfer events to that host.
Safe, long-term expression of clotting factors has been successfully achieved in large animal models of haemophilia using multiple gene transfer strategies, but these findings have not yet been translated into success in patients.
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The finding of multiple putative HGT DNAs that are shared between a human epidemic MRSA isolate and a contagious bovine mastitis S. aureus isolate, but that are absent from other S. aureus, indicates that these two phylogenetically distinct strains most likely have undergone multiple gene transfers either between themselves or with as yet unidentified additional bacteria.
Restricting the analysis to multiple gene transfers virtually guarantees that a LGT event took place.
This pattern suggests that the evolution of the phosphatase gene in the NCLDV involved multiple gene transfers and replacements.
For the Thermoprotei we identified 55 multiple gene transfers, of these, only 7 or 13% originated in non-thermophiles.
Six regions extremely variable because of multiple gene transfers from related species/strains have been distinguished in P. furiosus [ 19].
Furthermore, Alphaproteobacteria are thought to be mosaics, and they are known to have undergone multiple gene transfers [ 12].
More suggestions(15)
multiple gene function
multiple file transfer
multiple gene duplication
multiple gene modification
multiple methyl transfer
multiple embryo transfer
multiple mass transfer
multiple gene transformation
multiple source transfer
multiple gene order
multiple muscle transfer
multiple coherence transfer
multiple charge transfer
multiple block transfer
multiple layer transfer
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