Sentence examples for multiple gene rearrangements from inspiring English sources

Plethodontid salamanders show multiple gene rearrangements with likely concerted evolution on duplicated regions [ 108].

Conversely, the two other representatives of Onychophora (Podsiadlowski et al. 2008, Podsiadlowski et al., unpublished data; GenBank accession EF624055) display multiple gene rearrangements, autapomorphic for each species.

The multiple gene rearrangements distinguishing the IR of Marsupiomonas sp. from those of the two Pedinomonas taxa include the inversion of the entire rDNA operon.

It was found that the multiple gene rearrangements in the Chlamydomonas lineage resulted in an increased sidedness, i.e. an increased propensity of adjacent genes to be located on the same strand.

The ideal model system would provide multiple gene rearrangements for comparison (to identify common themes), but in a lineage that is not rearranging so frequently that hidden and convergent rearrangements obscure the interpretation of evolutionary events.

Although these gene blocks are quite primitive, as indicated by their presence even in other deuterostomes, their occurrence only in the Phallusia genus among all tunicates suggests that this may be the result of multiple gene rearrangements, rather than the remnant of a primitive gene order.

They showed the INC-sequence to be homologous for all genera from simultaneous analysis of nucleotides and gene order – a very difficult task for myctophids considering multiple gene order rearrangements and putative associated INC-sequences.

Alternatively, the chimeric structure of p42d might have been the result of multiple gene exchanges and rearrangements.

Patient #1 and Patient #2 demonstrated direct alterations in the PI3K/AKT/mTOR pathway (PTEN loss and PIK3CA mutation, respectively) in addition to multiple gene amplifications and additional rearrangements or mutations.

It thus differs from the adaptive immune system comprising B and T lymphocytes, in that it does not rely upon clonal selection of effector cells with unique antigen-specific receptors provided by rearrangement of multiple gene segments.

Suffice it is to say these approaches have already led to the identification of multiple novel splice variants [ 23], novel gene rearrangements [ 24, 25] and novel fusion genes [ 26, 27], and to the identification of read-throughs [ 27], which are RNA molecules resultant from the co-splicing of two genes that are contiguous in the genome in the absence of a structural genomic aberration.