To achieve this degree of resemblance to native nerve tissues, numerous physical, chemical, and biological factors have to be taken into consideration when incorporating multiple-functioning components into a nerve conduit [ 44, 45].
Mapping of predicted proteins from 24,962 BES to the UniProt database yielded 45,380 GO annotations as a result of multiple associations of individual predicted proteins with multiple functions, processes or components (Additional file 5: Table S5).
Mapping of predicted proteins from 86 candidate genes to the UniProtKB database yielded 1,035 GO annotations as a result of multiple associations of individual proteins with multiple functions, processes or components [ 40] (Additional file 4: Table S2).
In addition, the prospect of producing freeform device components using additive manufacturing at full scale allows designers to even further refine components to a specific purpose, or even integrate multiple functions into a single component.
44 LF, a major protein in human milk, performs multiple functions as an important component of innate immune defence against infections (table 3).
Bi-component fibers typically combine multiple functions that arise from at least two distinct components.
Using an example of a network component, we further showed that the enrichments of multiple functions were localized in distinct chromatin communities within a network component.
Several assembly proteins also appear to have dual functions and multiple functions and remarkably, multiple functions have also been observed for the structural peptide components of complex I (Elguindy & Nakamaru‐Ogiso, 2015).
Rational design of multi-component small-molecular metallophosphors, metallodendrimers and metallopolymers aiming at color tuning and multiple functions forms the major focus of this review.
The multiple functions of vitamin D in the immune system's response to infection suggest it may be an integral component in combating sepsis (Fig. 1).
