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With significant advancements in genetics, proteomics, cellular and molecular biology and biomaterials engineering, the nanomedicine strategies have become progressively refined regarding the modulation of surface and bulk chemistry of the nanovehicles, control of drug release kinetics, manipulation of nanoconstruct geometry and integration of multiple functionalities on single nanoplatforms.
With years, the design of nanoparticles (NP) is complexifying, allowing multiple functionalities on the same object [6]-[8].
Nevertheless, a growing need exists to create nano-based platforms that bear multiple functionalities on a single platform.
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Assigning multiple functionalities to a single button on an appliance help manufacturers economize user interfaces, but, this can easily create confusion for the users.
In addition, it allows us to easily incorporate multiple functionalities onto the same macromonomer, which is a gamechanger for our projects on drug delivery and imaging with bottlebrush and brush-arm star polymers.
Understanding the role of multiple functionalities in the reaction on catalytically relevant surfaces, particularly with regard to deoxygenation chemistry, is paramount.
This thesis aims to expand our current toolkit on functionalization to molecules that have multiple functionalities that can react with the surface.
Xing, L. et al. Self-healable polymer nanocomposites capable of simultaneously recovering multiple functionalities.
Moreover, individual solid-state plasmonic devices lack the ability to deliver multiple functionalities.
Cathelicidins have multiple functionalities.
Its multiple functionalities and tools are making LEAPdb a useful resource for the in silico exploration of the structure-function relationship of LEAP on the basis of their primary sequence as well as their various physicochemical properties.
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