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As Che proteins may take on multiple functional roles, it is to be noted that ignoring multiplicity of copies may have resulted in neglecting some interesting phenomena.
Agati, G. & Tattini, M. Multiple functional roles of flavonoids in photoprotection.
Bone morphogenetic proteins (BMPs) are members of the transforming growth factor-beta superfamily of proteins that have multiple functional roles in mammalian development.
The relatively high overlap cutoff (50%) between evolutionary and functional gene modules allows genes with multiple functional roles to be captured by different module types.
This discrepancy may be linked to the multiple functional roles of aspirin where its activity may largely depend on the in vivo microenvironment.
These antimicrobial peptides produced by neurons and microglia have been recently shown by our group to promote the regeneration of neurites in axotomized leech CNS [14], indicating that they have multiple functional roles in the CNS.
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Polymers are ubiquitous in living systems: for example, DNA and RNA are essential for storage and transcription of genetic information, proteins have multiple structural and functional roles in cells, and polysaccharides are used for energy storage, exoskeleton formation in animals and structural fibres in plants.
We show that each protein plays multiple functional and structural roles: Cas5c cleaves pre-crRNAs and recruits Cas7 to position the RNA guide for DNA binding and unwinding by Cas8c.
This finding indicated that these genes have multiple or different functional roles in response to different biotic stresses.
In eukaryotes, the cardiolipins (CL), a class of mitochondrion-specific anionic phospholipids, play multiple structural and functional roles in bioenergetics, mitochondrial signaling, and cellular fate pathways.
Using a binomial test, Bonferroni-corrected for multiple comparisons, the functional roles of the convergent network as a whole were identified by determining those BDs and PCs that showed a significant over-representation in experiments activating within the seed regions, relative to the entire BrainMap database (Laird et al. 2009b; Eickhoff et al. 2011).
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