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Nodes with multiple functional links represent "functional hubs".
In general, high first-order similarity suggests the existence of a functional link between two genes, and clustering based on the second-order similarity captures multiple functional links always activated and deactivated under similar conditions.
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Structural equation models or SEM [ 1, 2] are used to model multiple traits and functional links among them, which may be interpreted as causal relationships.
Some hub regions appeared to link multiple functional clusters (e.g. visual and sensorimotor) while others occupied central positions within a single functional cluster.
Unique positioning of survivin in cancer cells has enabled it to link together multiple functional molecular networks to promote aggressive behaviour (Kanwar et al, 2011).
This discrepancy may be linked to the multiple functional roles of aspirin where its activity may largely depend on the in vivo microenvironment.
In addition, we performed a co-expression network analysis using a database of mRNA gene expression profiles of multiple brain regions in order to explore potential functional links of calcyon to other genes.
If a cluster of gene pairs follows the same co-expression pattern across multiple cancer datasets, it represents a module of functional links being turned on or off simultaneously across different cancer phenotypes.
As a complement, we performed a co-expression network analysis using a database of mRNA gene expression profiles of multiple brain regions in order to explore potential functional links of calcyon to other genes.
ZnPc with symmetric and multiple functional groups, e.g., tetracarboxyphthalocyanine zinc, is easy to be prepared but is unfavorable for linking targeting agents due to many reasons.
The same viruses were prevalent in multiple body habitats within individuals, and these shared components of the individual's virome were consistent with anatomic or functional links between these body sites.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com