The reactive secretion of sTNFR1 by MSCs was also observed after treatment with neutralizing anti-sTNFR1 antibodies, suggesting that NFκB activation in MSCs is regulated by multiple, not necessarily redundant, functional cytokine receptors [ 151].
By modulating multiple functional immune cell types and their corresponding cytokines, EPO therapy transformed a significantly destabilized autoimmune process in EAE animals into one of relatively normal immune status.
The multi-level network used in this study revealed central proteins comprising multiple functional categories including transcription factors, signaling proteins, enzymes and cytokines.
Limited evidence for microbiome associations with genetic ancestry or kinship across multiple functional and taxonomic levels.
Deng, H. X. et al. Multiple functional groups of varying ratios in metal-organic frameworks.
Agati, G. & Tattini, M. Multiple functional roles of flavonoids in photoprotection.
In the real world, multiple functional units are involved in a single transaction.
Nodes with multiple functional links represent "functional hubs".
We focus on the roles of miRNAs in regulating TLR-signalling pathways by targeting multiple molecules, including TLRs themselves, their associated signalling proteins and regulatory molecules, and transcription factors and functional cytokines induced by them, at multiple levels.
Other receptors (NKG2D and TRAIL; Supplementary Fig. 5A) or functional cytokines (G-CSF, IP-10, MIG, CXCL5; Supplementary Fig. 5B) of NK cells were not differently expressed.
