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Vav proteins contain multiple function motifs and are involved in various cellular signaling processes, including cytoskeleton organization, calcium influx, phagocytosis, and cell transformation [ 3].
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These results indicate that the amino acid sequence of smMLCK encodes multiple functional motifs in addition to the catalytic domain.
APPL1 contains multiple function domains, including the Bin1/amphiphysin/rvs167 (BAR) domain, the pleckstrin homology (PH) domain, the phosphotyrosine binding (PTB) domain, and the CC motif (Deepa and Dong, 2009).
Multiple functions for Mcm2-7 ATPase motifs during replication initiation.
Typically, individual effector proteins have a modular architecture with several functional domains or motifs, which confer multiple functions onto the effector.
Therefore, while positional enrichment of motif location relative to start codons can be used as functional support when the motif is derived from genes of multiple functions, a high-degree of positional enrichment can also be used to identify a motif as a potential artifact if the genes come from a highly-duplicated gene family as is the case for antigenic variation genes.
Additionally, the actin-binding and PLP-binding motifs are critical for the multiple functions of PFN1, including actin elongation, polymerization, and dynamics, as well as for interactions with diverse ligands and binding partners (over 50 of which have been described)15,16,17.
We specifically include the RGD sequence in 1 because RGD, as the well-established functional tripeptide motif binding to integrins, can carry out multiple functions.
Multiple functions?
They serve multiple functions.
Multiple functions and essential to Ayurveda".
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