Sentence examples for multiple founder lines from inspiring English sources

Finally, the presence of multiple founder lines as well as wild derived inbred strains can be advantageous.

This effort is the most analogous to the current study due to the use of multiple founder lines.

Although the use of multiple founder lines introduces more alleles and decreases relative effect size, the process is much more analogous to human association mapping.

They are created by several generations of intercrossing among multiple founder lines.

Thus, making microinjection transgenic mice requires the analysis of multiple founder lines.

More recently, panels of multiway RILs have been developed that combine the genomes of multiple founder lines via an initial mixing stage followed by successive generations of inbreeding.

Synthetic populations cross multiple inbred founder lines for multiple generations to create a population whose genomes are mosaics of the original founder lines' genomes.

After obtaining multiple founder mice, lines displaying comparable levels of mutant or wild-type transgene accumulation were selected and backcrossed to C57Bl6 to establish the lines detailed in this paper.

The MCK-miR-133a-1 MCK-miR-133a-1 MCK-miR-133a-1 MCK-miR-133a-1lized mouse eggs and multransgenicsgeniconstruct lines wase obtainjected verintod by PCR genotyping.

Importantly, tumor nodules from multiple C/T790M mice from different founder lines do not appear to harbor secondary kinase domain mutations arising in cis.

The BC2F1 plants representing all the founder lines are generally used for developing BILs.