Your English writing platform
Discover LudwigSuggestions(2)
Exact(1)
Nevertheless, I suspect that epistatic phenomena should be pervasive in regulatory systems that have evolved a fine coupling of multiple feedback structures allowing for ultrasensitive responses, such as those switch-like dynamics that are defining features of most signaling pathways and transcriptional regulatory networks partitioning the embryo into discrete expression domains.
Similar(59)
Overall, I conclude that the phenotypic and fitness effects of multiple perturbations are strongly conditioned by both the regulatory architecture (i.e. pattern of coupled feedback structures) and the dynamic nature of the spatio-temporal expression trajectories displayed by the simulated networks.
Programmes that go to scale require multiple feedback loops, often overlapping.
Cells use multiple feedback controls to regulate metabolism in response to nutrient and signaling inputs.
As is common with any complex system, multiple feedback loops work within the system.
Bifurcation analyses on feedback loops indicate that multiple feedback loops are coordinated to modulate sporulation efficiency.
The Arabidopsis circadian clock is composed of multiple feedback loops.
However, these feedback structures do not ensure switch-like behavior.
Feedback structures are common regulatory structures in biological systems, especially in signaling pathways.
Classically, negative feedback structures are considered to confer stability, while positive feedbacks tend to have the opposite effect.
Furthermore, analysis of the feedback structures, which is also very common in signaling pathways, is conducted as an expansion to an original structures without feedback.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com