Our model for examining effects of chronic stress and pollution may aid future studies of multiple-exposure effects on various health outcomes (e.g., cardiovascular function) and may help to elucidate pathways through which social stressors (e.g., poverty, violence) may shape population susceptibility to pollution exposures.
The approach of assessing multiple exposures against multiple outcomes follows the principles of the Multiple Exposure Multiple Effects (MEME) Model [ 31], and aims to provide information that is more relevant to broader policy and program planning than can be achieved through studies focussed on specific exposures and specific outcomes.
Additionally, we did not adjust for other OCPs and PCBs because of the concern for collinearity, with resulting unstable coefficient estimates or lack of model convergence when estimating multiple correlated exposure effects with maximum likelihood estimation.
MICA allows for the comparison of multiple markers of exposure, effects, and susceptibility in asthmatic and non asthmatic children.
After all, these problems are characterized by multiple sources, multiple agents, multiple pathways, multiple exposure routes, multiple health effects, long delay periods between cause and effect, cross-bordering scale effects, etc.
A model that incorporates the idea of multiple exposures and multiple effects is being used increasingly (Briggs 2003).
It is also important to identify a population with a wide range of exposure concentrations for those key pollutants hypothesized a priori to be of interest in order to evaluate the relationships between the distributions of multiple exposures and observed effects.
It also enabled us to assess the effect which multiple exposure to this intervention would have on VCT, after adjusting for potential confounders or correlates.
Biomass burning is a process of combustion of organic matter that is characterized by a multielemental composition and size distribution [ 8, 9], representing a combined exposure to several pollutants and health effect associated with multiple exposure.
Researchers are also examining the effects of multiple exposures as well as the effects of exposures on vulnerable populations such as children and the elderly.
