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Although multiple experiments of the in vivo and the in vitro response to silica particles have revealed that fibroblasts are activated to produce more collagens and other extracellular matrix (ECM) components [24] [26], there is a lack of a mathematical model to quantify interactions among the molecules, and to predict dynamic behaviors of this bio-system.
It is possible to combine multiple experiments of the same platform type (Affymetrix or spotted) by merging probes using either their unique probe identifier (to combine data from two versions of the same platform), NCBI gene index (to combine data from the same organism on different platforms) or NCBI homologene id (to combine data from different organisms).
The goal of the working group was to mature the module to become an official part of Chado, fully consistent with its design principles and requirements, and as part of that expand its capacity for storing data from multiple experiments of specimens that were collected, treated and evaluated in various locations, environments and time points.
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We also carried out multiple experiments on networks of size ranging from 500 to 1000 nodes.
In the case of multiple IMS experiments and multiple mappings to the same atlas, one can compare the anatomical interpretations of multiple experiments to each other by using a common reference (atlas) space.
Results are expressed as mean ± SEM of n animals for in vivo experiments and mean ± SEM of multiple experiments for in vitro assays.
RNA samples (typically n = 3 to n = 5) were prepared from multiple experiments, each of which consisted of a consecutive series of time points.
The use of such a serial design with multiple experiments, instead of a single factorial design with a very large number of conditions, promised to give more reliable results.
In multiple experiments suppression of 4-5 genes resulted in variability in terms of reduction of each targeted mRNA.
As observed through the analysis of multiple experiments, the enrichment of the V0 subunit d was quite similar in early and late endosomes indicating that the density of the proton translocator subunit was the same in both compartments (not shown).
Quantitation of NRO hybridization signals by PhosphoImager analysis is based on the average of multiple experiments after subtraction of background signal, shown by probe M.
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