Your English writing platform
Discover LudwigSuggestions(5)
Exact(2)
Cassette events involving successive multiple exons have also been reported.
Phyluce was designed for the analysis of UCE data, and its adoption for analysis of single-copy genes where multiple exons have been targeted is inappropriate because exons are often assembled on separate contigs and phyluce views multiple contigs matching a targeted locus as an indication of paralogy (see Appendix S3 for further discussion).
Similar(58)
A large number of alternatively spliced genes that have multiple"variable" first exons have been identified in the human genome, including protocadherin (PCDH), UDP-glucuronosyltransferase (UGT), plectin (PLEC1), neuronal nitric oxide synthase (NOS1), and glucocorticoid receptor (GR) genes [ 1].
To identify these underrepresented poly(A) sites, we preferentially selected intronic single-block ESTs considering that ESTs that span multiple exons often have been included in known UniGene clusters and have been used for study of alternative splicing.
All genes with multiple exons must have a first and last exon.
Ritz et al. [ 26] suggested that this mechanism was used for generation of intraexonic deletions and deletions affecting multiple exons, which have been discovered in their study in the human SGCE gene, associated with the neurological movement disorder myoclonus dystonia.
Our analysis of orthologues of HOTAIR in 10 mammals covering multiple eutherian orders suggests that HOTAIR exons have discrete evolutionary dynamics, and that some exons evolved significantly faster in primates than in non-primate mammals.
Such 3' exons have a general tendency to be longer (51% of 3' exons in multiple-exon transcripts verified by Refseq mRNAs are ≥ 1000 nucleotides in length).
Multiple exon skipping has previously been shown to be associated with mutations in 5' as well as 3' splice sites in several genes [ 24].
There were 562 pairs that differed with the presence of an internal cassette exon in one of the isoforms (median length: 196.5), with 297 exons having lengths in multiple of 3's.
9,436 (96%) multiple-exon cDNAs have at least one intron occuring at exactly the same position on the cDNA when aligned to the S. lycopersicum and S. tuberosum genomes (panel A-c).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com