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Such an approach can also be used to integrate the CIO with legacy annotations, by imposing an arbitrary confidence statement to all single evidence lines (e.g. medium confidence from single evidence), and then automatically generating terms from the multiple evidence lines branch, thus providing confidence information at least according to the multiplicity and consistency of evidence lines.
Also, assertions annotated with the term 'rejected' should not be considered when aggregating multiple evidence lines.
Finally, the information provided by multiple evidence lines needs to be reconciled.
For this reason, we created the terms 'confidence statement from multiple evidence lines of same type' and 'confidence statement from multiple evidence lines of multiple types', where evidence type corresponds to any evidence term in ECO.
It is also different from conflicting multiple evidence lines, where each single evidence has not been directly invalidated.
This led us to create two branches in the ontology: a 'confidence statement from single evidence' branch' and a 'confidence statement from multiple evidence lines' branch.
Similar(48)
Multiple lines of evidence reveal the protective effects of hydrogen in various models of brain injury.
Multiple lines of evidence suggest that the BBB transport is absorptive endocytosis.
Multiple lines of evidence suggest that genetic factors play an important role in its etiology.
Multiple lines of evidence for the early transition to farming include macroscopic and microscopic plant remains and settlement patterns.
Multiple lines of evidence are now consistent showing that the climate sensitivity is very unlikely to be at the low end of the range.
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