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Meyer, D. & Birchmeier, C. Multiple essential functions of neuregulin in development.
Forest ecosystems are fundamental for the terrestrial biosphere as they deliver multiple essential ecosystem services (ES).
Trophoblast giant cells (TGCs) are one of the cell types that form the placenta and play multiple essential roles in maintaining pregnancy in rodents.
Polyphenol molecules play multiple essential roles in plant physiology such as defences against plant-pathogens and micro-organisms.
Here, we show that CRISPRi can also be used for fine-tuning prokaryotic gene expression while simultaneously regulating multiple essential gene expression with less labor and time consumption.
This should not be limited to the provision of a single GF but should instead release multiple essential GFs at an optimized ratio in a specific spatiotemporal mode.
This protein has multiple essential roles in the replication cycle involving RNA binding, viroplasm formation, helicase and can hydrolyse the γ-phosphate of RNA and NTPs acting as an RTPase and NTPase.
Remarkably, we also found that 13 out of the 24 mutations appear to be fast-acting, making them particularly useful for careful dissection of multiple essential requirements.
Ontogenetic habitat shifts by native reef fish lead to the use of multiple essential habitat types [40], [41], [42] and make protection of ecosystem functionality an important goal.
With conditional alleles, multiple essential requirements can be examined by shifting at different times from the permissive temperature of 15°C to the restrictive temperature of 26°C.
Furthermore, one gene can have multiple essential requirements during an organism life cycle, precluding investigation of all but the first essential requirement in progeny homozygous for a non-conditional mutation.
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