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Polyphenol molecules play multiple essential roles in plant physiology such as defences against plant-pathogens and micro-organisms.
Trophoblast giant cells (TGCs) are one of the cell types that form the placenta and play multiple essential roles in maintaining pregnancy in rodents.
This protein has multiple essential roles in the replication cycle involving RNA binding, viroplasm formation, helicase and can hydrolyse the γ-phosphate of RNA and NTPs acting as an RTPase and NTPase.
Microtubules play multiple essential roles in cells including forming the mitotic spindle, transporting vesicles and organelles, providing structural support as part of the cytoskeleton, and serving as platforms for the assembly of signaling complexes.
Wnt signaling in general plays multiple essential roles in organogenesis, carcinogenesis, and tissue homeostasis [ 11].
The relatively broad adverse physiological impact of severe Ni deficiency in both plants and animals hints of multiple essential roles.
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Replication protein A (RPA), a heterotrimer with subunits of molecular masses 70, 32, and 14 kDa (RPA70, RPA32, and RPA14, respectively), is a single-stranded DNA-binding protein with multiple and essential roles in almost every aspect of DNA metabolism, including replication, repair, and recombination [ 6].
The orphan nuclear receptor NR5A1 (also known as steroidogenic factor 1) plays essential roles at multiple levels of the reproductive axis and controls the gonadal expression of multiple genes that are essential for reproduction [13].
These results indicate that a single SSB tetramer must interact simultaneously with multiple protein partners during some essential roles in genome maintenance.
Wnt signaling is one of the most conserved pathways during evolution, playing essential roles in multiple biological processes like embryonic development and adult tissue homeostasis.
Wnt signaling pathways play essential roles at multiple steps of animal development, including embryonic induction, organogenesis, and adult tissue homeostasis.
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