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Despite the mechanistic possibility for catalysis, multiple equivalents of the promoter are often required in order to effect the reaction.
This observation is consistent with the multiple equivalents of SAM used, as well as with the mechanism proposed by Grove et al. (noted in section 7.1.2).
NosN is a class C methyltransferase that by analogy to HemN likely employs multiple equivalents of SAM as part of the catalytic mechanism (section 11.1.3).
On the basis of the ability of this system to tolerate multiple equivalents of water, we reasoned that the use of "undried" solvents ought to be achievable; impressively, the reaction could be performed very effectively in nonanhydrous commercial solvent even without any need for subsequent drying, degassing, or other purification.
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Recently, the batch equivalency of plug flow has been exploited to screen multiple equivalent batch reactions in a single experiment, minimising waste generation and reducing process development time.
8. Present multiple equivalent offers simultaneously (MESOs).
3. Make multiple equivalent simultaneous offers (MESO).
In mathematics there are many, many cases where there are multiple equivalent ways to define things.
For more information on the benefits of multiple equivalent simultaneous offers in negotiation, see also MESO Negotiation: The Benefits of Making Multiple Equivalent Simultaneous Offers in Business Negotiations.
When you present multiple equivalent simultaneous offers, or MESOs, you show other parties the issues you value most.
Fortunately, a versatile strategy exists that allows you to take the lead in the dance: multiple equivalent simultaneous offers, or MESOs.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com