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Entry into vacuoles occurs in multiple epithelial cell lines including AGS gastric adenocarcinoma, Caco-2 colon adenocarcinoma and MDCK kidney cell line, and depends on the actin cytoskeleton.
These studies have provided insights into specific gene regulatory networks that control lung progenitor cell fate and expansion, airway branching and differentiation of the lung progenitors into the multiple epithelial cell lineages.
TGF-β is a potent inhibitor of proliferation in multiple epithelial cell types, including alveolar type II cells [28].
The question how lack of pendrin affects fluid transport in the embryonic inner ear is complicated by the fact that pendrin is expressed in multiple epithelial cell types that are located in small domains throughout the inner ear.
TGF-β signaling inhibits proliferation in multiple epithelial cell types by influencing the expression of cell cycle regulatory proteins to induce arrest prior to the restriction point in G1.
Since TGF-β/Smad signaling is a major anti-proliferative pathway in multiple epithelial cell types, and is active in the postnatal mouse bronchiolar epithelium [34], we tested the effect of Sox2 on TGF-β1/Smad3 mediated gene transcription.
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Microerosions caused by multiple epithelial cells being shed from a single site revealing the lamina propria to the lumen is designated Watson grade III (structural defect).
Earlier studies have reported the presence of GABAergic receptors, specifically GABAA receptors, in multiple lung epithelial cell types [71], [72], [73].
HLOs possess organized proximal airway structures with apparently multiple differentiated epithelial cell types, as well as smooth muscle cells.
In several experiments using multiple breast epithelial cell preparations, lamin A/C down-regulation consistently resulted in 30%70%% of the cells having large and atypical nuclear morphology.
Expression of Sox17 in peripheral respiratory epithelial cells of the adult mouse lung reprogrammed mature alveolar type II cells toward multiple proximal airway epithelial cell lineages, supporting a role in regulating plasticity/progenitor cell behavior [13].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com