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This response includes an increased expression of glucose transporters and multiple enzymes responsible for a metabolic shift towards anaerobic glycolysis (Warburg effect), as well as the downregulation of mitochondrial respiration.
The model error was relatively small when multiple enzymes responsible for branching reactions were incorporated together (data not shown).
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The AMO is a membrane-bound, multiple-subunit enzyme responsible for the oxidation of ammonia to hydroxylamine, which is further converted to nitrite by the hydroxylamine oxidoreductase (Hyman and Arp 1992).
It is believed that the protein modification (e.g. post-translational cleavage) such as glycosylation, proteolysis or both could be responsible for the genesis of multiple enzymes [37].
The study thus provides further support for the notion that polymorphisms in genes for enzymes responsible for citrullination contribute to RA development in multiple populations of Asian descent.
The mechanisms responsible for the increased adiposity are changes in gene expression of multiple enzymes and transcription factors by the virus (8 – 15 ).
The expression of enzymes responsible for BCAA degradation, BCATs, exhibited a decrease by ALA-treatment.
Matrix metalloproteinases (MMPs) are a large family of proteolytic enzymes responsible for matrix degradation.
Heterogeneous xylan is a complex substrate, and it requires multiple enzymes to release its constituent sugars.
Lysosomal enzymes responsible for GAG degradation are defective in MPSs.
Arachidonic acid itself is catalyzed to biologically active metabolites by multiple enzymes, including cyclooxygenase and lipoxygenase.
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