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An interesting question is whether an intervention focused on multiple environments in preschool and family settings can balance children's EBRBs and also diminish SES differences in EBRBs.
Consequently, we made the assumption of multiple micro-environments within countries, and chose individual respondents as more likely to reflect these multiple environments in our analysis.
As most health habits are established in early childhood, we believe that an intervention at multiple environments in preschool and family settings can balance children's EBRBs and diminish SES differences in EBRBs.
Although each chemical environment i has a specific viable space V i (n), some genotypes in V i (n) must be viable for multiple environments, in particular at large n.
Therefore, a comprehensive needs assessment will more likely lead to effective behavioral changes because it concentrates on theory-driven, evidence-based factors across multiple levels and multiple environments in an intervention [ 13].
The difference between the interval mapping and the Bayesian mapping in the context of Q×E is that the Bayesian method uses a multivariate (multiple environments in this case) and multiple QTL model.
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Additionally the provincial-wide adoption of one QI program (RTC) in multiple environments (units in various Saskatchewan hospitals) gave us the opportunity to explore the impact of various unit contexts on RTC implementation.
The stable QTLs across multiple environments gained in this study enable incorporation of favorable alleles into agronomically superior germplasm by using technology of MAS combined with backcrossing method.
Involvement of younger children and the multiple environments targeted in the study (e.g., home, school) may decrease the likelihood of negative effects that have been demonstrated with bringing deviant children together in groups [ 36].
In addition to the simplification of genetic analyses, NILs are considered genetically 'immortal' [ 13] which allows for replicated experiments across multiple environments resulting in more accurate estimates of effect size for complex traits.
Furthermore, investigating the performance of genotypes across multiple environments, as in this study, allows calculation of genetic correlations among traits, the proportion of variance that two genetic traits share (Sgro and Blows 2004).
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