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In this study, a factorial design and multiple endpoint strategy have been used to evaluate the combined toxicity and possible interactions between the non-dioxin-like PCB 138 and the potent AhR agonists 2,3,7,8-TCDF 2,3,7,8-TCDF,2,3,7,8-PeCDD (PCDD).
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A multiple endpoints strategy can enhance the quality of risk evaluation of chemical compounds.
This protocol was based on the endpoint strategy.
Third, multiple endpoint analyses are demonstrated to validate the invasion.
Studies with several endpoints can be in multiple endpoint categories, studies comparing different drug management programs can be in multiple drug management program categories.
The invasive transition of DCIS in our lumen-based model was validated by multiple endpoint analyses.
We describe the use of multiple endpoints in the design, analysis, and interpretation of pain clinical trials, and review available strategies and methods for addressing multiplicity.
Developers can use Event Grid to route events to specific endpoints (or even multiple endpoints) and filter them as necessary.
Modern clinical trials are often complex, with multiple competing objectives and multiple endpoints.
However, conducting several independent studies to consider multiple endpoints and/or tissue compartments is resource intensive.
To better measure the overall impact of the intervention, individual endpoints as well as a global test of multiple endpoints are used.
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