Sentence examples for multiple end organ from inspiring English sources

These findings indicate that IL-1 is necessary for the development of nephritis in DBA/1 mice and suggest that the elevated IL-1 levels in these mice may be one reason why the DBA/1 strain is particularly sensitive to multiple end organ diseases.

Whereas c-mer knockout mice exhibited increased anti-dsDNA autoantibody levels without any significant renal pathology [ 43], Tyro3/Axl/Mer triple-knockout mice exhibited high levels of autoantibodies along with multiple end organ involvement [ 44].

The recognition of these antigens by their cognate antibodies and the resultant deposition of immune complexes leads to the development of a chronic inflammatory state, which can have devastating effects on multiple end organ targets including the kidneys, the cardiovascular system, the skin, and the central nervous system.

Evaluate the multiple end-organ targets affected by intradermal testing (IDT -based IDT -basedapy.

This might be important when recording nerve activity from a mixed nerve innervating multiple end-organs to increase the modality selectivity for the nerve fibers of interest.

Preeclampsia is a condition of pregnancy characterized by systemic endothelial dysfunction, multiple end-organ ischemia, hypertension and proteinuria - a phenotype that is largely recapitulated by systemic inhibition of TGF-β and VEGF in pregnant rats [17].

Of the 118 patients with severe sepsis, 44 patients had respiratory dysfunction, 69 patients had renal dysfunction, 34 patients had hepatic dysfunction, 33 patients had cardiovascular dysfunction, and 45 had multiple end-organ dysfunction.

For patients with multiple end-organ dysfunction, global response at end of treatment (Table 2 and Figure 1) was 76.2% for anidulafungin and 29.2% for fluconazole (P < 0.05; 95% CI, 21.3 to 72.8).

Finally, limitations regarding the use of death certificate data have been well described (7, 20, 38), and the presence of multiple end-organ complications is common in individuals with longstanding diabetes (39); for example, CAD is rare in the absence of underlying renal disease in individuals with young-onset diabetes, particularly type 1 (40).

3 4 Moreover, comorbidities associated with psoriasis such as the metabolic syndrome can contribute to damage in multiple end-organs and often leads to markedly impaired QoL as well as early mortality.

Multiple end-stage organ injury after AKI may worsen the severity of infection in severe sepsis.