Sentence examples for multiple effector mechanisms from inspiring English sources

These data demonstrate that multiple effector mechanisms including H2A ubiquitination and chromatin compaction combine to mediate PRC1-dependent repression of genes that are crucial for the maintenance of ESC identity.

So the lymphocyte populations provide multiple effector mechanisms capable of eliminating the R. equi infection.

pDCs are considered as the most potent "natural IFN-producing cells" [27] and, through production of this cytokine, they might activate multiple effector mechanisms of the immune system, including T cells, B cells and NK cells [3].

These transformed epithelial cells eventually acquire the multiple effector mechanisms of metastasis [ 17].

It has also been shown that the anticancer response of the SR/CR mice involves multiple effector mechanisms [ 3].

The cytolysis of cancer cells in SR/CR mice was previously indicated to involve multiple effector mechanisms [ 1- 3], a number of which are associated with innate immunity.

This situation necessitates the use of very high levels of therapeutic compounds in order to achieve both multi-pathway and multiple effector mechanism inhibition.

Since the knockouts of perforin, superoxide and nitric oxide alone did not abolish the anticancer ability of the SR/CR mice, then the production of SR/CR mice with multiple effector mechanism knockouts may also be necessary for more complete characterization of the SR/CR phenotype.

A major obstacle hindering the definition of Treg cell suppressive action is their apparent multiple and redundant effector mechanisms (Miyara and Sakaguchi, 2007).

From these results, it is likely that only global immunosuppression, affecting multiple leukocyte populations and their effector mechanisms, would be able to abolish the SR/CR phenotype.

As anticipated from the previous studies, within these pathways we find Ubx targets at multiple levels from ligands to receptors and effector mechanisms (Figure 2).