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The separation between two aircrafts is a process which depends on multiple dynamic interactions between pilots.
Complex diseases result from multiple, dynamic interactions among various factors at different spatiotemporal levels, and the classical or reductionist approach of treating one disease in isolation and as if it has one origin is greatly challenged by a high degree of biocomplexity.
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As an intermediate step, a visual immunoprecipitation assay was developed that allowed direct observation of multiple, dynamic protein interactions on immobilized, distinguishable beads in cell extracts.
Proteins with β-propeller folds participate in diverse cellular functions and serve as platforms for multiple dynamic protein protein interactions.
Evidence is provided from a detailed case study, where the actions of the auditors have been followed in their efforts to make the military activities auditable by focusing on the multiple and dynamic interactions between them, the auditee and others.
Insulin-like growth factor (IGF) and insulin (INS) proteins orchestrate a regulatory network of multiple components with dynamic interactions, named herein the IGF/INS axis.
The multivalent architecture of its actin binding domain led us to hypothesize that cortactin may find branch junctions by diffusing along actin filaments through multiple weak and dynamic interactions, similar to the actin binding protein VASP (Hansen and Mullins, 2010).
However, etiology of complex diseases involves multiple pathways and their dynamic interactions with environmental factors (Sing et al., 2003; Zerba et al., 1996).
Combining measures of multiple variables and their dynamic interactions in response to time and specific treatments often increases the sensitivity and specificity of these monitoring modalities to identify specific disease processes and quantify whether therapy is effective or not.
For example, non-Gaussian peaks due to fronting or tailing are a challenge in chromatography and arise from multiple sub-populations of dynamic interactions between the analyte and stationary phase.
If we accept the argument that a mono-centric governance model is unlikely to promote effective conservation actions for endangered species such as the bridled nailtail wallaby, then some form of decentralised coordination is required to ensure that the dynamic interactions between multiple actors across multiple forums does lead to good conservation outcomes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com