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The trend in cancer-drug development is toward multiple drugs with specific molecular targets.
PharmaCube is creating new technology to 3-D print pills that contain multiple drugs, with a focus on helping heart attack patients who must take multiple drugs with shifting dosages.
People over the age of 65 are already likely to take multiple drugs with potential interactions and are most likely to suffer dangerous adverse reactions.
With the aim of codelivering multiple drugs with different characteristics, immiscible and miscible liquids were utilized to fabricate nanoparticles of polyvinylpyrrolidone/poly(lactic-co-glycolic acid) (PLGA) and poly(ε-caprolactone)/PLGA with distinct core shell structure by coaxial electrospray.
Due to its unique configuration, the microchip exhibits some appealing characteristics, such as being able to supply single or multiple drugs with precise small doses, ability to achieve pulsatile release mode, small in size, and good biocompatibility, and thus has the potential for application as implantable device in the field of controlled drug release.
"You can release multiple drugs with different release profiles.
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AD is a neurodegenerative disease with complicated pathogenesis, therefore therapy with multiple drugs or drugs with polypharmacological activities will likely be the best approache to address the varied pathological aspects of the disease.
It can be difficult to cure these complex diseases effectively with Western medicines by using the "one disease, one target, one drug" approach, and there are growing expectations toward the "one disease, multiple targets, multiple drugs" approach with multi-effective drugs such as traditional medicines used in combination therapies with Western medicines.
Thus, I can avoid taking multiple drugs (polypharmacy) with the newer preparations.
Use of multiple drugs, interaction with cardiopulmonary disease, and the absence of reported cases are limitations of the system.
The study found that people who took multiple drugs associated with a possible increased risk of depression were also more likely to be depressed, but researchers couldn't distinguish whether the medications were the cause.
More suggestions(15)
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com