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The proposal of natural pectin nano-platform for delivery of multiple drugs is critical for biomedical research, especially a particle size of below 100 nm with high yield.
A fourth of those ages 18 to 39 regularly take two prescription drugs, the report noted, suggesting that a reliance on multiple drugs is no longer confined to older Americans.
This new platform for multi-drug localized delivery can be easily fabricated, tuned, and translated to a variety of implant applications where control over spatial and temporal release profiles of multiple drugs is desired.
Studies on the pharmacological properties of multidrug ABC transporters (reviewed in [1], [19], [22], [23]) revealed that the ability of these systems to transport multiple drugs is based on direct drug-protein interactions.
106 Use of multiple drugs is common in older adults.
Resistance to multiple drugs is the consequence of an accumulation of mutations[ 3].
Similar(42)
More remarkable still, he said, Tamiflu is still the only drug useful against avian influenza, "and we all know that one drug is not adequate to treat any viral disease," he said, noting that multiple drugs are used in AIDS.
Adverse effects brought on by the combination of multiple drugs are thought to be responsible for nearly a third of all hospital admissions.
Their predictions of bacteria's growth in the presence of multiple drugs were accurate even in cases where the measured, apparent interaction of the multidrug combination was qualitatively different from that of the pairwise interactions.
Challenges and opportunities associated with fabrication of stratified multilayer films capable of multi-stage delivery of multiple drugs are also discussed.
"This could be useful in developing new combination therapies, where multiple drugs are used simultaneously to treat a cancer by attacking different parts of the cancer cells at the same time".
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